Excerpt: “This standard operating procedure (SOP) provides implementation guidance on integration of HIV and syphilis testing services with mpox testing. This is relevant as part of broader emergency response efforts for countries experiencing increased case reports and outbreaks of mpox. This integrated approach is intended to improve early detection and management and to enhance and streamline services. The focus is on procedures for ensuring that HIV and syphilis testing are conducted when individuals are tested for mpox. This also includes conducting additional testing and laboratory evaluations for people diagnosed with HIV (or re-engaging in care) as well as those diagnosed with syphilis. This SOP outlines the steps for coordinating efforts with key stakeholders, including the ministry of health and current partners, laboratories and private-sector entities. This SOP applies to health care professionals, laboratory staff and partners involved in implementing testing and treatment.”